Image Registration Based on Thin-Plate Splines and Local Estimates of Anisotropic Landmark Localization Uncertainties
نویسنده
چکیده
We present an approach to elastic registration of tomographic brain images which is based on thin plate splines and takes into account landmark errors The inclusion of error information is important in clin ical applications since landmark extraction is always prone to error In comparison to previous work our approach can cope with anisotropic er rors which is signi cantly more realistic than dealing only with isotropic errors In particular it is now possible to include di erent types of land marks e g quasi landmarks at the outer contour of the brain Also we introduce an approach to estimate landmark localization uncertainties directly from the image data Experimental results are presented for the registration of D and D MR images
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